The Hardesty laboratory is focused on identifying mechanisms of compromised liver regeneration and treatment options that restore liver regeneration and liver function in alcohol-associated liver disease (ALD) and steatotic liver disease (SLD). Liver diseases are thought to persist due to chronic inflammation that goes unresolved preventing liver regeneration. This is a common feature in multiple end-stage liver diseases for which there are no adequate treatments or therapies. Below are some ongoing projects in the Hardesty Lab