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Thomas Sabo, II

Assoc Professor

School of Medicine

Orcid identifier0000-0002-9573-145X
  • Assoc Professor
    School of Medicine

BIO

The unifying theme of my research concerns elucidating the relationship between biomolecular motion, structure, and functionality. My fascination with these concepts was initially cultivated during my graduate studies under the mentorship of Muriel Maurer at the University of Louisville. This invaluable graduate experience was a significant stepping-stone to my post-doctoral studies with Christian Griesinger at the Max-Planck Institute for Biophysical Chemistry (MPI-BPC) in Göttingen, Germany. It was here where I honed my skills in applying Nuclear Magnetic Resonance (NMR) spectroscopy for characterizing the amplitudes, the timescales, and the nature of motion within biomolecules. In February of 2015, I established my independent career at the Brown Cancer Center, University of Louisville (UofL) with a primary focus on applying the techniques and methodology that I have developed toward anti-neoplastic targets and on providing researchers with the tools necessary to characterize structurally silent, yet functionally important, conformational states. The idea is to eventually exploit these “alternative” structures and functional dynamics as unique targets for future drug development efforts.

ACADEMIC POSITIONS

  • Associate Professor
    University of Louisville, Louisville, United StatesJan 2023
  • Assistant Professor
    University of Louisville, Louisville, United StatesFeb 2015
  • Endowed Chair - James Graham Brown Foundation Chair in Cancer Biophysics
    University of Louisville, Brown Cancer Center, Louisville, United States1 Nov 2025

DEGREES

  • PhD
    University of Louisville, Louisville, United States

POSTGRADUATE TRAINING

  • Postdoctoral Fellow
    Max Planck Institute for Biophysical Chemistry, Germany
    Postdoctoral Research