Thomas Sabo, IIProfile page
Assoc Professor
School of Medicine
BIO
The unifying theme of my research concerns elucidating the relationship between biomolecular motion, structure, and functionality. My fascination with these concepts was initially cultivated during my graduate studies under the mentorship of Muriel Maurer at the University of Louisville. This invaluable graduate experience was a significant stepping-stone to my post-doctoral studies with Christian Griesinger at the Max-Planck Institute for Biophysical Chemistry (MPI-BPC) in Göttingen, Germany. It was here where I honed my skills in applying Nuclear Magnetic Resonance (NMR) spectroscopy for characterizing the amplitudes, the timescales, and the nature of motion within biomolecules. In February of 2015, I established my independent career at the Brown Cancer Center, University of Louisville (UofL) with a primary focus on applying the techniques and methodology that I have developed toward anti-neoplastic targets and on providing researchers with the tools necessary to characterize structurally silent, yet functionally important, conformational states. The idea is to eventually exploit these “alternative” structures and functional dynamics as unique targets for future drug development efforts.
ACADEMIC POSITIONS
- Associate ProfessorUniversity of Louisville, Louisville, United StatesJan 2023
- Assistant ProfessorUniversity of Louisville, Louisville, United StatesFeb 2015
- Endowed Chair - James Graham Brown Foundation Chair in Cancer BiophysicsUniversity of Louisville, Brown Cancer Center, Louisville, United States1 Nov 2025
DEGREES
- PhDUniversity of Louisville, Louisville, United States
POSTGRADUATE TRAINING
- Postdoctoral FellowMax Planck Institute for Biophysical Chemistry, GermanyPostdoctoral Research