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Yoannis Imbert-Fernandez

Assoc Professor

School of Medicine

BIO

Yoannis Imbert-Fernandez, PhD,  is an Assistant Professor in the Division of Medical Oncology/Hematology, School of Medicine at the University of Louisville. Dr. Imbert-Fernandez is a scientist with an interest in understanding the molecular events leading to resistance to anti-cancer therapies, particularly as it relates to breast cancer. She received a Bachelor of Science from the Department of Biochemistry, University of Havana, Cuba in 1993 and a Ph.D. in Biochemistry and Molecular Biology from the University of Louisville in 2010. She completed a postdoctoral fellowship in the Division of Medical Oncology/Hematology at the University of Louisville in 2015. Her basic and translational research integrates diverse approaches to elucidate genetic and metabolic mechanisms underlying resistance to targeted therapies and to design novel therapeutic regimens to minimize recurrence. Ongoing translational studies in her laboratory focus on the study of molecular alterations promoting drug therapy resistance in breast cancer. This is achieved by performing transcriptomic and metabolic analysis of drug resistant breast cancer tumors. Using this approach, her laboratory has identified key vulnerabilities of drug-resistant tumors that can be exploited to design novel therapies that may extend survival and ultimately change the outcome of metastatic breast cancer patients. Dr. Imbert-Fernandez has published in journals such as JBC and Cancer metabolism. She is serves as a standing member for the NIH Mechanisms of Cancer Therapeutics A study section.  

ACADEMIC POSITIONS

  • Endowed Chair - Brown-Forman Chair in Cancer Research
    University of Louisville, Brown Cancer Center, Louisville, United States1 Aug 2025
  • Associate Professor
    University of Louisville, Medicine-Division of Medical Oncology and Hematology, Louisville, United States2022
  • Assistant Professor
    University of Louisville, Medicine- Division of Medical Oncology and Hematology, Louisville, United States1 Oct 2015 - 30 Jun 2022

DEGREES

  • PhD
    University of Louisville, Louisville, United States2005 - 2010

POSTGRADUATE TRAINING

  • Post-Doctoral Research Associate
    University of Louisville, Medicine, Division of Medical Oncology and Hematology, Louisville, United States2010 - 2013
    Targeting Breast Cancer with PFKFB3 InhibitorsPostdoctoral Research
  • Post-Doctoral Scholar
    University of Louisville, Medicine, Division of Medical Oncology and Hematology, Louisville, United States2013 - 2015
    Targeting Breast Cancer with ER, CDK4/6 and PFKFB3 Inhibitors